Antiaris toxicaria article about antiaris toxicaria by. The complete chloroplast genome of antiaris toxicaria, a. The latex contains varying amounts of cardiac glycosides and can be very poisonous. Cardiac glycosides from antiaris toxicaria with potent cardiotonic. List of various diseases cured by antiaris toxicaria. One significant difference within the species is that the size of the fruit increases as you travel from africa to polynesia. Antiaris toxicaria is a tree in the mulberry and fig family of. The database and code is licensed under a creative commons attributionnoncommercialsharealike 3. It can also be substituted for terminalia superba engl. The genome was 161,412 bp in length, comprising a large singlecopy region lsc of 89,883 bp, a small singlecopy region ssc of 20,375 bp, and a pair. Bmc res notes anticonvulsant effects of antiaris toxicaria aqueous extract. Text is available under the creative commons attributionsharealike license.
Antiaris article about antiaris by the free dictionary. The plant list does not attempt to include all infraspecific taxa. How antiaris toxicaria is effective for various diseases is listed in repertory format. Pdf evaluation of genetic diversity in antiaris toxicaria. Chromatographic methods were used to isolate and purify the chemical constituents. Author links open overlay panel xiaosan li a mengjie hu b jie liu b qian liu a zhixing huang a shunlin li c xiaojiang hao c xiaokun zhang b xinsheng yao a jinshan. Antiaris toxicaria palta north 24 parganas 20120411 9602.
The absolute configuration of sugar unit was defined by acid hydrolysis and appropriate derivatization. Useful tropical plants database 2014 by ken fern, web interface by ajna fern with help from richard morris. Right now there are 404 articles and 1,254 registered users on this wiki. Bioassayguided fractionation of the extract led to identification of nine new cardiac glycosides 1. Antiaris toxicaria is a tree in the mulberry and fig family, moraceae. Ipo, upas, antiaris toxicaria, sacking tree herbal medicine an illustrated compilation of philippine medicinal plants by dr godofredo umali stuart with botanical information, chemical properties, folkloric uses and research studies. Antiaris toxicaria is a tree in the mulberry and fig family of moraceae. The seed extract was analysed on c 18 column utilizing water and acetonitrile as mobile phase under isocratic elution at 220 nm, therefore this method can be used for standardization by estimation of.
The name of the upas tree has become famous from the mendacious account professedly by one foersch, who was a surgeon. Five new cardiac glycosides 15, namely antiaroside yzc together with 19 known compounds were obtained from the bark of antiaris toxicaria. Schum and can be used as a substitute for the latter. Their structures were established using ms and nmr spectroscopic studies, including. Pdf a new cytotoxic 19norcardenolide from the latex of. The preliminary phytochemical screening in different solvent extracts of antiaris toxicaria leaves, collected in the area anaikatti, coimbatore district exhibited variations in the presence of phytocompounds depends upon the polarity of solvents, the methanolic extract showed the presence of all phytoconstituents except alkaloids. Ipo, antiaris toxicarias, sacking tree herbal medicine. Several of the cardiac glycosides induced apoptosis in lung cancer cells, which. Antiaris toxicaria has previously shown anticonvulsant activity in acute animal models of epilepsy. The seed extract was analysed on c 18 column utilizing water and acetonitrile as mobile phase under isocratic elution at 220 nm, therefore this method can be used for standardization by estimation of convallatoxin, a cardenolide in antiaris toxicaria. The present work aims to develop and validate a reversedphase high performance liquid chromatography hplc method for quantification of convallatoxin in antiaris toxicaria leusch. All structured data from the file and property namespaces is available under the creative commons cc0 license.
Cardiac glycosides from antiaris toxicaria with potent. Antiaris e um genero botanico pertencente a familia moraceae. Their chemical structures were determined by ir, hresims, 1d and 2d nmr hsqc, 1 h 1 h cosy, hmbc, roesy. A new norcardenolide, named toxicarioside h 1, was isolated from the latex of antiaris toxicaria pers.
There were a total of 3 compounds isolated from antiaris. Files are available under licenses specified on their description page. An ethanolic extract of antiaris toxicaria trunk bark showed potent in vitro cardiotonic effect on isolated. One significant difference within the species is that the size of the fruit increases as. Antiaris toxicaria in the germplasm resources information network grin, u. Antiaris toxicaria moraceae a new distribution record to the eastern ghats. Bioassayguided fractionation of the extract led to identification of 9 new cardiac glycosides 19, named antiarosides ai, antiarotoxinin a 10, and 18 known compounds. Just type a new title, click go, and near the top of the results page, there will be a link to create the new page. This page was last edited on 22 august 2018, at 21. Animal models used include maximal electroshock test mest. Files available from the acs website may be downloaded for personal use only. Moraceae aqueous extract in rodents priscillakolibeamante,1 donatuswewuraadongo,1 ericwoode,1.
Evaluation of genetic diversity in antiaris toxicaria lesch. It has a remarkably wide distribution in tropical regions, occurring in australia, tropical asia, tropical africa, indonesia, philippines, tonga, and various other tropical islands. Icr mice and spraguedawley rats were pretreated with aae 200800 mg. To study the chemical constituents of the antiaris toxicaria lesch leaves. The only species, antiaris toxicaria is found throughout the old world tropics, from west africa to madagascar, and in sri lanka, india, indochina, southern china, thailand, throughout the malesian region, the pacific east to fiji and tonga, and northern australia. Antiaris toxicaria, pharmacognostic, leaf microscopy, anatomical sectioning. Antiaris toxicaria moraceae was evaluated for anticonvulsant activity in rodents.
Compound 1 showed significant cytotoxicity against k562, sgc7901, smmc7721, and hela cell lines in vitro by mtt method. Creative commons attributionnoncommercialsharealike 3. Peripheral neuropathy is a common neurologic disease that accounts for a lot of physician visits aims. Antiaris toxicaria herb uses, benefits, cures, side.
Its structure was elucidated on the basis of hrfabms and spectroscopic techniques ir, uv, 1d and 2d nmr. Antiaris toxicaria lesch welcome to pilikula nisarga dhama. The effects of the cardiac glycosides on apoptosis and the expression of orphan nuclear receptor nur77 were examined in human nihh460 lung cancer cells. Uses, benefits, cures, side effects, nutrients in antiaris toxicaria. The genome was 161,412 bp in length, comprising a large singlecopy region lsc of 89,883 bp, a. Guide to trees of papua new guinea copyright held by the authors, national herbarium of new south wales, and papua new guinea. There are five or six species in the tropics of asia, africa, and madagascar. The genus antiaris was at one time considered to comprise of several species, but is now regarded as just one variable species which can be further divided into five subspecies. Names of antiaris toxicaria in various languages of the world are also given. Reaches a height of 120 to 150 ft with a straight, cylindrical bole clear to 70 ft. Structural features of the purified compounds were identified by analyzing the physicochemical properties and spectroscopy characteristics. Antiaris toxicaria herb uses, benefits, cures, side effects. There are several recognized subspecies, but only subsp.
Increase in latency to seizures as well as reduction in duration and frequency of seizures indicated. An ethanolic extract of antiaris toxicaria trunk bark showed potent in vitro cardiotonic effect on isolated guinea pig atria. A new cytotoxic 19norcardenolide from the latex of antiaris. Apr 26, 2017 antiaris toxicaria has previously shown anticonvulsant activity in acute animal models of epilepsy.
Its seeds are spread by various birds and bats and it is not clear. Antiaris toxicaria is one of such medicinal plants with a remarkably wide distribution in tropical regions. One significant difference within the species is that the size of the fruit increases. Anticonvulsant effects of antiaris toxicaria aqueous. The genus antiaris was at one time considered to comprise several species, but is now regarded as just one variable species which can be further divided into five subspecies. Este artigo sobre a ordem rosales, integrado no projeto plantas e um esboco. Jul 23, 2010 an ethanolic extract of antiaris toxicaria trunk bark showed potent in vitro cardiotonic effect on isolated guinea pig atria. Antiaris toxicaria aqueous extract therefore possesses anticonvulsant activity. Antiaris toxicaria article about antiaris toxicaria by the.
To evaluate the efficacy of a ghanaian herbal product prepared from the stem bark of antiaris toxicaria subsp. You can also create new pages using the search box. Distributed throughout the high forest zone of west, central, and east africa on widely varying sites. Antiaris toxicaria antiaris, moraceae is a medicinal and extremely toxic species. One significant difference within the species is that the size of the fruit. A new cytotoxic 19norcardenolide from the latex of.
Antiproliferative cardiac glycosides from the latex of. Iita headquarters pmb 5320, oyo road, ibadan 200001, oyo state. Quantification of convallatoxin in antiaris toxicaria. Department of agriculture agricultural research service. The leaf is used to remedy various ailments but the.
Pdf antiaris toxicaria moraceae a new distribution record to. Cardiac glycosides from the bark of antiaris toxicaria. Upas, a javanese word meaning poison, and specially applied to the poison derived from the gum of the anchar tree antiaris toxicaria, a member of the figfamily moraceae, and a native of the sunda islands, which was commonly used to envenom the darts of the natives. To facilitate species identification and provide genetic information, we determined the complete chloroplast genome of a. This page was last edited on 22 december 2019, at 09. In russian literature the name anchar, or upas tree, refers to a. Phytochemical investigation of the latex of antiaris toxicaria resulted in the isolation of 15 new antiarosides jx 115 and 17 known cardiac glycosides. A new cytotoxic 19norcardenolide from the latex of antiaris toxicaria. Jpg vinayara 30 january 20 creative commons attributionshare alike 3. The genus antiaris was at one time considered to be comprised of several species, but is now regarded as just containing the one variable species antiaris toxicaria which can be further divided into five subspecies. Anticonvulsant effects of antiaris toxicaria aqueous extract. The aqueous extract aae was further investigated for activity in kindling with pentylenetetrazole and administration of pilocarpine and kainic acid which mimic temporal lobe epilepsy in various animal species. A taxonomic genus within the family moraceae the upas tree.